In any case, the SAM and BAM file are equally useful for identifying the polymorphisms that exist between a sequenced and a reference genome as well as with a third genome also aligned on the same reference, or even a fourth, a fifth and so on. These are extremely useful file as they are produced by the process of aligning (or mapping) reads on a reference genome, this is also called re-sequencing, although in my opinion this term is a bit misleading. In fact, today we talk about SAM file, or Sequence Alignment Map file, and its cousin BAM file, Binary Alignment Map file. I have decided to delight you with a new article that will go straight into the column "Files in bioinformatics", in which I talk about the most common and important file types used by bioinformaticians.
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